Citrus fruits belong to the family of Rutaceae which is one of the most important fruits crops of the world and it is consumed mostly as fresh produce or juice because of its nutritional value and pleasant flavor. Citrus is an excellent source of many nutrients that are able to supply a healthy diet. Phenolic acids and flavanones are the two main groups of phenolic compounds in citrus fruit juices. Generally all citrus juices are a rich source of antioxidant compounds, specifically phenol, flavonoids and ascorbic acid. The phenolic compounds have a wide range of biological activities such as antioxidant activity, protection against coronary heart diseases, anti-inflammatory, anticancer and antimicrobial activities.
Due to their important health-promoting properties, there is a growing interest to incorporate these compounds into food products, either to create functional foods or else to simply replace commonly used synthetic food additives such as butylated hydroxytoluene and butylated hydroxyanisole in order to prevent the side effects. There can be no doubt that nutritional value and pharmacological properties of different parts of indigenous fruits.
So, the regular consumption of phenolics rich fruits and vegetables along with the foods will inhibit the carcinogenesis and mutagenesis in humans. Among the juices three juices from citrus fruits (oranges included) contained significant total phenolics that increase antioxidant intake in human diet.
In this present study, juice samples from indigenous fruits of demonstrated that they are not only possesses antioxidant and radical scavenging activity but also exhibited excellent inhibitory potential against α-amylase, α-glucosidase, acetylcholinesterase, tyrosinase and β-glucuronidase in vitro. Consequently, citrus juices those are rich in sources of phenolics and flavonoids, are suitable and promising for the development of safe food products and natural additives. Hence, it may be concluded that the antioxidant and inhibitory potential against α-amylase, α-glucosidase, acetylcholinesterase, tyrosinase and β-glucuronidase action of citrus fruit juices could be used for future therapeutic medicine from the presence of potential neutraceuticals. Further studies will be conducted to identify bioactive constituents, molecular mechanisms involved in antioxidant activity, determination of their efficacy by in vivo studies and demonstration of their safety and effectiveness in clinical trials. Reference: http://www.sciencedirect.com/science/article/pii/S2213453014000044
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